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Following the genomic road map

first_imgOK, we’re part Neanderthal, and not that much different from chimpanzees after all. We also know that some drugs won’t work on my cancer, even though they might work on yours.And, if you want to find out what your DNA has been saying behind your back, the price of having your personal genome decoded is dropping like a stone.The map of the human genome, completed in 2001, has wowed scientists in the years since, even if the scale of its impact has not matched some of the early predictions surrounding the project.Eric Lander, a leader of the Human Genome Project, said Tuesday (Feb. 22) that he has been surprised at the pace of advances stemming from the project, which has been likened to “biology’s moon-shot.”“This has gone so much faster than I ever imagined,” said Lander, president and director of the Broad Institute of Harvard and MIT and professor of systems biology at Harvard Medical School. “We’ve been able to read out the lab notebooks of evolution.”Lander was part of a panel of scientific experts who talked about the Human Genome Project and its legacy at Sanders Theatre.The event, “Mapping the Human Genome: Ten Years After,” was hosted by Harvard President Drew Faust and webcast by USA Today. Other panelists were Margaret Hamburg, head of the U.S. Food and Drug Administration; M. Susan Lindee, chair and professor of history and sociology of science at the University of Pennsylvania; Vamsi Mootha, associate professor of systems biology and of medicine at Harvard Medical School and associate member of the Broad Institute; and Vicki Sato, former president of Vertex Pharmaceuticals and today professor of the practice of molecular and cellular biology in the Faculty of Arts and Sciences and professor of management practice at Harvard Business School.“Has sequencing of the human genome been transformative, and in what ways?” Faust asked in her introductory remarks. “How are we all … different than we otherwise would have been and what will the coming decades hold?”The Human Genome Project started in 1990 and involved scientists from 20 centers in six countries. At a cost of $3 billion, the first draft of the genome was published in 2001 and the full sequence was published in 2003. The resulting map shows 21,000 genes that provide the instructions for making a human being and provide the foundation for better understanding our basic biology, how we differ from other animals, and what happens when things go wrong.Lander reeled off a list of advancements made possible by the project. In barely the time it takes to get a single drug developed and approved for use in humans, the number of genes tied to common diseases such as diabetes and Alzheimer’s has increased from just 20 to 1,100, with more on the way. Scientists have decoded the genomes of dogs, chimpanzees, laboratory animals, and a host of other creatures. The cost of reading a genome has fallen dramatically in just 10 years. Technology today can do in five minutes a decoding task that would have taken a year to complete a decade ago, Lander said.The revolution extends to students and young researchers, who have at their disposal not only a new understanding of the foundation of life, but an array of equipment and techniques that didn’t exist not long ago.“They have the tools to do things today that it used to take armies to do,” Lander said. “My expectations have been blown away.”When it comes to the public’s expectations, however, hype surrounding the project may have led some to imagine an era of rapidly developed genetic cures, Sato said.Instead, as our understanding has advanced, the complexity of many diseases has emerged.But that’s not to say the Human Genome Project hasn’t had an effect on some illnesses, Mootha said.“I’m really excited about the future. If I were a student or graduate student, I don’t think there’s a better time to embark on biomedical research.”One problem, Mootha said, is that there is a “tsunami” of data from all the genetic analysis going on, so much so that equipment can’t handle or even store it.Another problem is the nature of the information, Lindee said. Though people are getting more information about their genetic tendencies, some of the information is ambiguous and difficult for doctors and patients to interpret, leading to an increase in what she called “uninformative information.”Sato said it has taken time for pharmaceutical companies to change how they operate to take advantage of a flood of genomic data. They have had to change the way they look at disease, but they also have gained a better understanding of the differences between patients, and the fact that certain medicines work better on some people than others.“If they have a mutation, we know this drug won’t work even though it is the same cancer [as another person without the mutation],” Sato said. “So much has changed in a relatively short period of time, I can’t imagine what the medicine of the future will look like.”last_img read more

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Menacing mice

first_img“Grass, brush and woody areas around our homes provide nesting places for mice,” he said. “But they leave these nests and search for warmer habitats like inside our homes.”That’s not black rice Most homeowners don’t know they’re harboring mice until they find evidence of mouse droppings, which resemble black grains of rice. Another telltale sign is chew marks on food containers and packages. The first thing to do to rid your home of mice, he said, is take away their food source. Keep garbage cans covered and food items stored in tightly sealed containers. This includes pet food. Use cheese or peanut butter to bait the trap and check and reset traps often. By Sharon OmahenUniversity of GeorgiaAs temperatures begin to drop, Georgia’s climate finally resembles what some call winter. It’s enough to drive people indoors to stay warm, and some unwanted guests, too. “Mice can occasionally venture in this time of year looking for warmth,” said Jim Crawford, a University of Georgia Cooperative Extension agent in Jefferson County. “It only takes a small crack or an open door to get an uninvited houseguest.” “Always position a trap so the trigger is next to the wall,” he said. “This way you get them from either direction if they’re running along the baseboard.” Make sure all doors seal tightly and window and door screens are in good shape. Use caulk to seal cracks around pipes and utilities where mice can slip into homes.Avoid using baitsDon’t use baits unless you feel you have to. “Baits can pose a threat to small children and pets,” he said. “Besides, mice will consume the poison and die behind walls and in other unreachable places and cause a terrible odor.”center_img The best way to get rid of mice, he said, is still the old-fashioned mouse trap. Traps should be placed next to walls, under furniture, in the pantry or behind the stove. Next, remove any weeds, trash, boards, firewood or other debris located near the exterior of your home. “These objects provide excellent cover for mice in the winter and snakes in the summer,” he said. Like many county agents this time of year, Crawford receives calls from homeowners who want to prevent mice from invading their homes, or they want to know how to get rid of them once they do. Crawford’s advise this year comes from experience. He recently gave chase to a mouse that escaped down a floor vent. “I stapled some dental floss to a baited mousetrap and lowered it very slowly into the duct until it disappeared from view,” he said. “I tied the other end of the string to the leg of the nightstand. Sure enough, the little varmint was hungry.”last_img read more

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Germany’s aba sides with European Council on IORP II risk evaluation

first_imgProvisions for EIOPA approval of pension scheme transfers and for risk assessments to include ESG matters should be among others left out of the final version of the new EU directive on occupational pension funds (IORP II), according to aba, the German pension fund association.The association, like others, set out its key demands for the negotiations between the European Parliament, the European Commission and the European Council on the revision of the directive.The trialogue started on Monday.The Parliament’s proposed version of IORP II was the last to be developed, via the Economic and Monetary Affairs Committee (ECON), which voted on it in late January. The preliminary date for the plenary of the Parliament is 10 May, according to aba. The association set out its main priorities for the negotiations yesterday, doing so in relation to the ECON’s proposal for the dirctive.  It makes six main demands, relating to matters such as risk evaluations for pensions and the holistic balance sheet (HBS), the rules for transfers of pension schemes, and the rules for the calculation of technical provisions.According to aba, the ECON’s version of IORP II would allow for the introduction of the HBS “through the back door”.It has therefore called for the Council’s position on “risk evaluation for pensions” (REP), the term aba prefers, to be adopted.It said the ECON and Commission’s version of Article 29 (on risk assessment) were unclear and that the requirements could therefore in practice develop into the HBS, “in particular when EIOPA adds further guidelines”.The implementation details of the risk-evaluation requirements should be left to member states, as per the Council’s text, and “there should be no room for EIOPA guidelines, which could then potentially result in a harmonised quantitative approach for the whole EU”.PensionsEurope this week called for the European Insurance and Occupational Pensions Authority (EIOPA) to develop principles-based guidelines instead of an HBS approach, while the Dutch Pensions Federation expressed a similar view.Both are strongly opposed to the HBS and potential associated solvency requirements.The aba’s position on the risk-evaluation requirements for IORPs is at odds with those of several, seemingly mainly UK-based responsible investment organisations, as the German association has called for the deletion of an article in the ECON proposal that recommends pension funds take into account “new or emerging risks, including risks related to climate change, use of resources, the environment, social risks and risks related to the depreciation of assets due to regulatory change”.  “A sensible implementation of the rule by IORPs is not possible,” the aba said.UK responsible investment charity ShareAction and 11 other civil society organisations are soliciting support from the European Council for the ECON’s language on integrating ESG factors into investment risk management.No to EIOPA say on transfersThe aba has also opposed an ECON amendment to the Council IORP II proposal relating to calculating technical provisions of liabilities (discount rates).Specifically, it called for the removal of the word “current” inserted before a reference to the requirement that market yields of specified types of bonds should be taken into account when determining the interest rate to be used.The ECON proposal’s provisions for calculating technical provisions based on market value would be harmful for German IORPs, according to aba.It would, for example, lead to results showing significant underfunding, in particular if a nearly risk-free interest rate term structure is used, as was the case in the EIOPA stress tests, and higher volatility. “IORPs have organised their whole structure along a valuation with a fixed tariff discount rate – a change is not that easily possible,” said aba.“That the market interest rate temporarily falls under the interest rate in the business plan does not mean that, in the very long run – which characterises occupational pensions – the promised benefits permanently cannot be financed.”Some other pension industry participants have given mixed feedback on the significance of the specification that the market yields to be taken into account should be “current”.One source thought the amendment was “rather innocuous”, and that the directive had always given a choice of market or expected yields, while a UK policy specialist told IPE it was unclear exactly what the wording meant, or what difference it might make.The German association also called for the final IORP II Directive to differ from the ECON’s version in relation to certain pension scheme transfer aspects.“The rules on the transfer of pension schemes as proposed by the ECON Committee in Article 13 and in the new Article 3a are neither adequate nor will they work in practice,” the aba said.Article 3a should be removed, it said, as it would give inappropriate new powers to EIOPA, namely to approve transfers of pension schemes.“No competencies that can be better addressed by national authorities should be transferred to the EU supervisory authority EIOPA,” it said.If a complete deletion of Article 3a is not possible, it added, then “the future EIOPA involvement ‘at the request of the competent authorities’ should at least be limited to systemic risks”. (aba own emphasis)Concern about Article 3a, on “duty of care”, is also shared by others.Philip Shier, senior actuary at Aon Hewitt* in Dublin, told IPE the article was a late-stage amendment and that the additional assessment by EIOPA “seems unnecessary” and could be viewed as hurdle by those considering transfers.The aba, meanwhile, said a requirement to be fully funded – as proposed in Article 13, paragraph 1 – is only justified for cross-border transfers of pension schemes but not transfers within a member state.Another change called for by the aba is the deletion of all ECON additions regarding intergenerational balance “because this cannot be achieved through supervisory law”.last_img read more

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Derby Charge Two Players for Drink-Driving and Crash

first_imgDerby: Derby County, an EFL Championship football side, have charged two of their players with drink-driving following a car crash that left team captain Richard Keogh with a season-ending knee injury. According to an ESPNFC report, Derby said in a statement that Mason Bennett and Tom Lawrence have been fined “the equivalent of six weeks’ of their wages and will serve an additional 80 hours of community and rehabilitation, which will include a drinking awareness course. BBC quoted the club as saying that it “will not tolerate any of its players or staff behaving in a manner which puts themselves, their colleagues, and members of the general public at risk of injury or worse, or which brings the club into disrepute.” The incident took place on September 24 when Keogh was reportedly in the back seat of a car that crashed into a lamppost. Bennett said: “Being a footballer and someone who young fans look up to I know the example I set is key. I am ashamed. At 23 I am old enough, and I was brought up, to know better.” (IANS) Also Read: Former England captain Wayne Rooney to Join Derby County as Player-cum-CoachAlso Watch:Durga Puja 2019 : ISRO Themed Durga Puja Pandal at Chatribarilast_img read more

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Sport in 2019: Twelve big moments

first_imgFILE PHOTO: Eliud Kipchoge becomes first person to run a marathon under 2 hoursParis, France | AFP | The action was spectacular, exciting and colourful for 12 months around the globe, but the thrilling and sometimes surprising images also caught the wider significance of modern sport.Megan RapinoeMegan Rapinoe lapped up the rapturous reception when the US women’s football team appeared in New York on July 2 two days after winning the World Cup. Rapinoe stood out on and off the field in France. She talked eloquently with her boots as she captained the United States and finished as the tournament’s joint top scorer. Off the field, Rapinoe, a campaigner for LGBT rights and gender equality, spoke out, attracting even wider attention as she stood up to President Donald Trump which did not diminish the reception she received when the team returned home.Siya KolisiSiya Kolisi stood tall as he showed off the Rugby World Cup trophy at a victory parade in Soweto on November 7. Kolisi, South Africa’s first black captain, had led the Springboks to victory five days earlier in Yokohama. Less than a month after Chester Williams, the sole non-white in South Africa’s first World Cup triumph in 1995 died at 49, Kolisi, prop Tendai ‘The Beast’ Mtawarira and wingers Cheslin Kolbe and Makazole Mapimpi were key members of the team.LiverpoolLiverpool did not walk alone as they won Europe’s top club competition for the sixth time. A tepid final in Madid was effectively settled by a controversial penalty award in the second minute. After that Tottenham were powerless against a defence martialed by the magisterial Virgil van Dijk. The most memorable moment came at home at Anfield in the semi-final on May 1 when the Reds, trailing 3-0 from the first leg deficit, beat mighty Barcelona 4-0. The Kop roared and their team responded.Lewis HamiltonLewis Hamilton had something to spare as he clinched his sixth Formula One driver’s title at the US Grand Prix with two races left in the season. Mercedes started strongly, winning the first six races, with Hamilton taking four of them. Even when the Ferraris were faster and their 21-year-old starlet Charles Leclerc collected four straight pole positions, Hamilton kept finding a way to win. He ended the season with 11 victories in the 21 races to collect a third straight title. He is now just one world title behind the all-time mark of Michael Schumacher.Eliud KipchogeEliud Kipchoge’s run on October 12 in a Vienna park might have been carefully stage managed, yet it was still a momentous and emblematic feat. The Kenyan became the first person to complete a timed run over the marathon distance in under two hours. After narrowly missing in 2017, he beat the symbolic mark by almost 20 seconds. He also bettered the world record by two minutes but did not break it. Because he ran behind a pace car, was escorted by a rotating phalanx of pace makers and had no competition, the official record remains a relatively leisurely 2:01:39, set by Kipchoge in Berlin 2018.Simone BilesSimone Biles sparkled again at the gymnastics world championships in Stuttgart in October. She won five more golds to take her tally to a record 25. Biles unveiled two fresh and complex elements, sparking debate after the international gymnastics federation assigned the moves relatively low values arguing that they did not want other gymnasts to endanger themselves imitating the American. The triumph came in a tough year which saw Biles speak about being abused by former US team doctor Larry Nassar. The 22-year-old American has suggested that she will retire after the Tokyo Olympics next year. Tiger WoodsTiger Woods showed he still has claws as he tore through the field on the final round at the Masters on April 14 to win his first major in 11 years. The 43-year-old Woods started the final day clad in his famous Sunday red and two shots behind Francesco Molinari. Over the last seven holes, five other men held or shared the lead. Only Woods held his nerve as he won his 15th major and fifth Masters. The rest of the season was more of the struggle, but Woods had proved he can still perform on the biggest SundaysBen StokesBen Stokes stooped to conquer. Returning to the England team after a ban following a brawl in 2017, he started the World Cup with runs, wickets and an astonishing catch to win man of the match. From there, his year just got better. In the final against New Zealand, he made 84 not out to earn England a tie, helped by a bizarre incident when he was hit by a fielder’s throw as he dived for a run, deflecting the ball for four overthrows. England won on tiebreak. Stokes was man of the match. In the Ashes, he clobbered an unbeaten 135, to claw England back from the brink in the third Test at Headingley.Steve SmithSteve Smith climbed off the canvas to eclipse even Stokes in the Ashes. The former Australian captain, also returning from a ban, was flattened by England fastest bowler Jofra Archer in the second Test and missed the third, the ‘Stokes Test’. But he still finished the series with 774 runs in four Tests — 333 more than the next highest scorer, Stokes — at an average of 110.57 as he ground down England’s bowlers and ensured Australia drew the series and retained the Ashes.Djokovic, Federer, WimbledonNovak Djokovic and Roger Federer pushed the limits as they fought out a dazzling heavyweight men’s final at Wimbledon. At 4 hours, 57 minutes it was the longest Wimbledon final. It only ended as soon as it did because of the first ever fifth-set tie-break in a Wimbledon final. Djokovic retained his title, 7–6, 1–6, 7–6, 4–6, 13–12, after saving two championship points. It was his 16th Grand Slam title. Only Federer (20) and Rafael Nadal (19) have more. Between them the three have now won the last 12 Grand Slams.JapanJapan were refreshing hosts at the World Cup. They brightened the competition with their high-energy running rugby, upsetting both Ireland and Scotland to reach the last eight for the first time  before bowing out to eventual winners South Africa in the quarter-finals. Indeed, their bowing also attracted attention. Japanese teams and fans have acquired a reputation for tidying up after them selves when they play away. As hosts, they also set a good example, as other teams copied their habit of bowing to fans.Lindsey VonnLindsey Vonn finished her career by collecting yet another medal. The American speed queen said her body was too battered to continue her pursuit of Ingemar Stenmark’s record of World Cup victories, but at the end of another injury-hit season she was still quick enough at 34 to claim an eighth World Championship medal in the downhill in Are, Sweden. She skied 19 seasons and won 82 World Cup races, both records for women. She won races in five disciplines and she always brought style and elan to events.Share on: WhatsApplast_img read more

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Scalise leads, but England’s Briggs is close behind

first_img28 Jun 2017 Scalise leads, but England’s Briggs is close behind Italy’s Lorenzo Scalise shot eight-under 64 on the Old Course at Walton Heath today to lead a low-scoring charge in the first round of the European Amateur Championship. Scalise, the Italian national champion, is just a shot ahead of England teenager Toby Briggs and South Africa’s Keegan de Lange, while Jeremy Gandon of France and Australia’s Dylan Perry both scored 66. Another English player, Daniel O’Loughlin (Ruddington Grange, Nottinghamshire), shares sixth place on 67. English amateur champion Dan Brown (Masham, Yorkshire) and St Andrews Links Trophy winner Matthew Jordan (Royal Liverpool, Cheshire) are both in the top ten with rounds of 68.   They’re all at the head of a thoroughly international leaderboard which features 29 players with scores in the 60s, including the host club’s David Boote on 69. In total, 60 players broke par, taking advantage of the still conditions and the softening effects of yesterday’s deluge. Scalise (pictured top) got off to a “perfect start” when he birdied the first, drove the par four 3rd to set up another birdie and had a tap-in birdie on the fourth. “From there I kept on playing with the same rhythm and I was never in the position of having to recover, except on the last hole.”  On the 18th, Scalise’s drive ended in thick rough. He powered it out and although he couldn’t clear the bunker guarding the green, he managed to get up and down for par to complete a bogey-free round. Briggs, a 17-year-old England boy international from Dunston Hall, Norfolk (pictured right), would have caught the leader but for a three-putt on the 18th. “I was about 30ft away and wanted to hole it for a birdie but I went about 6ft past and missed it coming back,” he explained. Earlier he’d holed several putts of around 30ft and pitched in for an eagle three on the 16th. “I’m happy after last week at the Amateur when I struggled off the tee and missed the cut. Today I wasn’t great of the tee but I had some good breaks and hit nearly every green in regulation. I’m looking forward to tomorrow.” De Lange matched Briggs’ 65 with a bogey-free round which was perhaps even more notable for including no score greater than four. “The key to the round today was the putter, it really hotted up,” he said. “I hit myself into a bit of trouble on the back nine and missed the fairway on all three par fives, but I birdied all of them with some really good putts.” He added: “I’ve played lovely and had a great day. I haven’t played well in a while, I’ve been a little on the back foot, so it’s nice to get a good round in.” The back nine was also kind to Gandon, who came home in six-under 31 for his 66. He had started well, quickly getting to two-under, before a double bogey on six pulled him back to level. On the 10th his round took off with the first of five birdies and an eagle, before he bogeyed 18. “I loved it!” he said of his round. Dylan Perry arrived at Walton Heath after finishing runner-up in last weekend’s Amateur Championship – but he was determined to put the disappointment behind him and he proved it with his 66. The 22-year-old Australian remarked: “It was a disappointing end result for me but I’ve got to take the positives. You can’t dwell on it for too long, you either come out of it a better golfer or go the other way, so it’s been a big confidence boost for me.” Today he started with two bogeys but quickly repaired the early damage, reaching the turn at one-under before coming back in five under 32, with the help of an eagle three on 16 and three birdies. “I’m all about being patient on the golf course, that’s how I play – and I played solid from 3 to 18! It’s only round one, but I’m looking forward to tomorrow,” he said. The 2016 champion Luca Cianchetti began the defence of his title with two under 70 and remarked: “It’s pretty good to be here to defend the title and I will do my best to take it home another time.” There’s much discussion within golf these days about pace of play and the first group out today set a great example. Robert MacIntyre of Scotland, Maximilian Schmitt of Germany and Stuart Grehan of Ireland were round in 3hr 45mins and all played under par, scoring 68, 69 and 70 respectively. In total, the whole field of 144 players played the 7180-yard course in the allotted time of 4hr 18min per group. England Golf Championship Director James Crampton said: “This is a great achievement and something we should applaud. Congratulations to the players.” Click here for full scores Images copyright Leaderboard Photographylast_img read more

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Allderdice captures City League title

first_imgby Malik VincentFor New Pittsburgh Courier Allderdice head coach Andre McDonald preaches defensive toughness to his players. If you ask anyone on his staff or someone he’s coached, he swears by it. So much, that the Dragons have proudly sported “HAWK-D” on their warm-ups for the past five years, and this season on their uniforms. But they aren’t the only ones who do.“It was uplifting to hear the entire student body chanting HAWK-D,” McDonald said. “It was really motivation to our guys to play the best game that we could.” ‘HAWK-D’—The Allderdice boys celebrate with the championship trophy after defeating Perry 73-63 in the City League championship game March 5. (Courier photo/William McBride/File) Led by senior Cameron Bailey’s 22 points and Eric Mallinger’s near triple-double, Allderdice (12-4, 17-7) won its second consecutive City League boys basketball Championship over top-seeded Perry, 73-63, at Peabody High School March 5.“It was a great contest,” Bailey said. “But I have to give much credit to our coaching staff, they had a great scouting report and they did everything they could to get us prepared for battle.”Perry had been the favorite to win it all after surrendering one conference game all year and defeating Allderdice in both of their regular season meetings.“I realized we needed to be prepared this time,” McDonald added. “We broke down the film from the last four meetings and made sure that we were going to come out and compete at our highest level.”Junior guard Justin Dobbs added a game-high 23 points for the Dragons but admits that he got off to a slow start.“My shot was off early so I eventually got to a point where I was just trying to get to the foul line.” Dobbs said. “We started to run the pick and roll and once that happened, I was fortunate enough to start making good decisions with the basketball.”Mallinger finished with nine points, 11 blocks, and 16 rebounds.“I knew that the offense was going to come,” Mallinger said. “I take pride in doing what I need to do on the defensive end. The coaches and I don’t even need to discuss that. I just try to go out there every game and crash the boards, as well as to make plays on defense.”Perry’s normal leading scorer, Marcus Smith, was held to only 10 points for the Commodores (15-1, 21-4). They were led by Bruce Grover’s 19 points and Greg McGhee’s 16, 11 of which he converted from the free-throw line.“We set out to build a strong program from top to bottom,” Allderdice assistant coach Jason Rivers said. “We’re the only team in the city that has a ninth grade program that feeds into our junior varsity, and goes into varsity. These kids do a tremendous job to get prepared to come up and win in this level.”(Reprinted from the March 9, New Pittsburgh Courier.)last_img read more

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ECHO EDDIE STAKES QUOTES – SATURDAY APRIL 9, 2016

first_imgJOCKEY QUOTES NOTES: The victory gave D’Amato a 39-34 lead over Doug O’Neill in the Winter Meet trainer standings with one racing day remaining. PHILIP D’AMATO, TOUGH IT OUT, WINNER: “​This is just a tremendous feeling. Mike Mitchell (his late mentor) and Nick Alexander, we wouldn’t be here if it wasn’t for them.” Winning owner/breeder Nick Alexander resides in Los Angeles.-30- TRAINER QUOTES FERNANDO PEREZ, TOUGH BUT NICE, SEVENTH: “He bumped me so hard on the backside, the number 5. He was four wide, and he’s still bumping me, so that took everything away from my horse. Absolutely.” JOE TALAMO, TOUGH IT OUT, WINNER: “We had a good trip. Phil just told me to ride him like Kent Desormeaux on Exaggerator, so we stayed in the five path and went from there. I thought the track was pretty fair for the first few races, and these last few you can come from behind; it feels great.”last_img read more

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UBER ONCE AGAIN THE ‘OFFICIAL RIDE’ TO SANTA ANITA PARK; USERS NOW RECEIVE 50 PERCENT OFF TO AND FROM THE GREAT RACE PLACE

first_imgARCADIA, Calif. (Jan. 19, 2017)–Uber and The Great Race Place are once again putting fans first, as those who travel to and from Santa Anita via Uber will receive 50 percent off of their fare.As the “Official Ride of Santa Anita Park,” fans using the Uber/Santa Anita promotional code SANTAANITA2017, with a maximum of $20 off each way, per visit, this is a terrific way to “go racing” from throughout the metro LA area.This 50 percent discount promotion is available to fans for an unlimited number of visits through closing day, July 4.Uber, which has become a way of life for millions nationwide, offers everyday low prices utilizing a wide variety of available vehicles, from low cost models to high end luxury. Uber drivers use their own vehicles and come from all walks of life and the Uber experience has been designed with safety and security as top priorities.The official Santa Anita/Uber pick-up and drop-off zone is located at the track’s Club House East entrance gates. For additional information, please visit santaanita.com, or call (626) 574-RACE.last_img read more

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Road group pleas with rally fans to respect the roads

first_imgThe Donegal Road Safety Working Group (DRSWG) is appealing to everyone attending the Joule Donegal International Rally this weekend to stay safe on the roads and to be respectful of everyone using the roads.This appeal comes as rally organisers join forces with Donegal Joint Policing Committee and An Garda Síochána to encourage all those attending the rally to ‘Respect the Rally’ and comply with a few simple rules.These are to drive safely & respect other road users; never drink and drive; respect residents; keep noise levels down at all times; keep the race in its place and; take your litter home. Brian O’Donnell, Road Safety Officer said the DRSWG is committed to promoting road safety.He said “Large numbers will arrive in Donegal to attend the rally and also to enjoy everything Donegal has to offer and we want to emphasise the importance of safety, both on the rally course and on the public roads.“Followers of the rally need to be reminded to watch the stages from safety areas, always stay within the speed limits and drive at a speed appropriate to the weather conditions and allow plenty of time to arrive safely at your destination.“Unfortunately there are also those who drive dangerously and who have no interest in the rally and are only intent in causing trouble for the Gardai and ordinary members of the public who use the roads. We would appeal to everyone attending the rally, that safety on our roads is paramount and should always takes precedence above everything else. Please, keep the race in its place”. Keep the Race in its place – that’s the message being promoted by Donegal Road Safety Working Group and the Donegal Joint Policing Committee for this weeks Joule Donegal International Rally. Picture includes Cathaoirleach Cllr. Nicholas Crossan, Inspector Michael Harrison, Donegal Road Safety Working Group, Brian O’Donnell, Donegal Road Safety Officer, Brian Brogan, Donegal Motor Club, Cllr. Gerry McMonagle, Donegal Joint Policing Committee, Seamus Neely, Donegal County Council with members of the Donegal Motor Club and Donegal Youth Council. Photo Clive WassonInspector Michael Harrison said An Garda Síochána is appealing to all those coming to County Donegal for the rally weekend to show respect for residents in Donegal and not engage in anti-social behaviour on the roads.He added “We have a major policing operation in place and those found breaking the law will be dealt with in the appropriate manner. Our objective is to have a weekend where there are no fatal or serious injury collisions. We will be testing drivers for drink and drug driving and finally I would ask everyone using the roads not to speed, never to use a mobile phone while driving, always wear a seatbelt and never drink or drug drive.”Cllr Gerry McMonagle Chair of the Donegal Joint Policing Committee is looking forward to welcoming rally enthusiasts to Donegal saying that “these messages are about making sure that the rally can be enjoyed by spectators and locals in a safe and respectful way”.“This rally is unique to Donegal and is the only 3-day tarmac rally in Ireland and the UK. The rally organisers do a great job year in year out organising this top class event and we in the Joint Policing Committee and Donegal County Council want to lend our support to them by helping to share a few simple messages so that the rally can be thoroughly enjoyed by visitors and locals alike.”Road group pleas with rally fans to respect the roads was last modified: June 18th, 2019 by StephenShare this:Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to share on Pocket (Opens in new window)Click to share on Telegram (Opens in new window)Click to share on WhatsApp (Opens in new window)Click to share on Skype (Opens in new window)Click to print (Opens in new window) Tags:donegalGardaiRallytrespectROADSWarninglast_img read more

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